From the American Veterinary Medical Association
1. Abnormal Swellings that persist or continue to grow
2. Sores that do not heal
3. Weight loss
4. Loss of Appetite
5. Bleeding or discharge from any body opening
6. Offensive odor
7. Difficulty eating or swallowing
8. Hesitation to exercise or loss of stamina
9. Persistent lameness or stiffness
10. Difficulty breathing, urinating, or defecating
